Automated Tyrer-Cuzick 8 Breast Cancer Risk Assessment in Your EHR
The CancerIQ TC8 Calculator runs Tyrer-Cuzick 8 — the version most widely recognized by insurers for breast MRI eligibility — to return BRCA1/BRCA2 mutation probabilities and breast cancer risk by age, including 10-year and lifetime, directly inside Your EHR. It's built to help breast centers identify eligible high-risk patients and guide them to appropriate next steps, guideline-aligned with NCCN.
06/09/2026 at 1:03 PM
06/09/2026 at 1:03 PM
TC8
NCCN Criteria
Trusted by 60+ Health Systems Across 275+ Clinical Locations
What the TC8 Calculator does
Precision Risk Model
Runs Tyrer-Cuzick 8 (the default) and returns BRCA1/BRCA2 mutation probabilities plus personal and population breast cancer risk by age, including 10-year and lifetime. TC8 with competing mortality (TC8CM) is also available.
Guideline-Based Flagging
Optionally flags whether the patient meets NCCN HBOC genetic-testing criteria (Yes/No). This tool does not evaluate Lynch syndrome or other NCCN guidelines.
EHR-Embedded
Runs directly inside your EHR, so results land in the patient's chart automatically.
Accreditation-Ready
Supports NAPBC accreditation and program compliance needs.
Fits the workflow you already have
The TC8 Calculator connects directly into your EHR and runs as part of the workflow your team already uses. CancerIQ hosts and maintains the connection, so your team isn't writing or hosting the calculation service, and results return straight to the patient's chart.
IT team looking for exact interface, operation, and credentialing details? Find them in the FAQ here →

Why Health Systems Choose CancerIQ for Their Risk Calculator
A hosted, governed connection your IT team can actually implement — backed by licensed clinical content and a proven track record with enterprise EHR teams.
- A clear, documented implementation process. CancerIQ provides the interface specifications, credentialing requirements, testing plan, and implementation guidance your team needs upfront. Responsibilities are clearly defined, so IT knows what it must configure, what CancerIQ hosts, and who owns ongoing maintenance.
- Experience working with enterprise EHR teams. Our team has a proven track record working across health system IT, interface, security, clinical informatics, and operational stakeholders. We understand the technical review and change-management processes required to move an EHR-integrated clinical tool from evaluation through production.
- One governed connection across departments. The same Risk Query (HL7v3) connection can support Radiant, Ambulatory, and other EHR workflows. Breast imaging, OB-GYN, and additional clinical teams can use a consistent risk engine without each department standing up its own integration.
- A fully hosted and maintained risk engine. CancerIQ hosts the underlying service and maintains the risk logic. Your EHR team configures its built-in interface — no custom SOAP service to build and support, and no standalone system outside Epic that forces staff to manually re-enter data between two separate screens.
- Licensed clinical content with accountable governance. CancerIQ is an official NCCN HIT licensee and uses a licensed, current version of Tyrer-Cuzick Version 8. Your organization has clear documentation of the model and guidelines being applied, rather than relying on an internally recreated calculation or an undefined black box.
- Designed to support accreditation requirements. The solution establishes a consistent, documented risk assessment protocol aligned with NAPBC requirements and similar standards, helping programs demonstrate a repeatable process during accreditation review.
- Straightforward, competitive pricing. If you're evaluating another solution, share a documented quote and we'll match or beat it for comparable scope.
Frequently Asked Questions
FOR CLINICAL TEAMS
What is the Tyrer-Cuzick 8 (TC8) model, and how is it different from earlier versions?
Tyrer-Cuzick 8 is the current iteration of the Tyrer-Cuzick (IBIS) breast cancer risk model, and is the version most widely recognized by insurers for breast MRI eligibility decisions. CancerIQ's TC8 Calculator is licensed to run this specific version — it's the default model for the TC8 Calculator.
Does this integrate with my EHR?
Yes. The TC8 Calculator runs directly inside Your EHR through a connection CancerIQ builds and hosts, so results appear in the patient's chart automatically. If you're the one configuring it, the exact technical specifications are in "FAQ — for your EHR build/IT team" below.
What guidelines does the TC8 Calculator align with?
The TC8 Calculator's risk flagging is designed to align with current NCCN guidance on breast cancer risk assessment and high-risk screening eligibility — this refers to the TC8 Calculator specifically, not CancerIQ's platform broadly.
Who is this built for?
Breast centers, health systems, and imaging programs that need to identify high-risk patients at scale from family history already in the chart — without adding manual chart review.
How does CancerIQ's pricing compare to other risk assessment vendors?
We don't believe cost should be the reason a program can't run a validated, EHR-embedded risk assessment. If you're evaluating another vendor, bring us their documented quote — we'll work to match or beat it for comparable scope.
How do I see it in action?
Book a personalized demo below. We'll walk through the calculator in a workflow that matches your program, and follow up with a custom implementation and pricing overview.
FOR YOUR EHR/IT TEAMS
Do we need to build or host our own interface for this?
No. CancerIQ hosts the HL7v3 Risk Query SOAP endpoint. On the EHR, your team configures the built-in Family History / Risk Query interface to call it — you don't write or host the risk-engine service.
What interface do we configure?
Risk Query — Outgoing Family History (OutgoingTS_FamilyHistory). The SOAP operation is GetRiskDataWithLicenseAsXML. CancerIQ hosts that endpoint and issues WS-Security credentials; your EHR team points the interface at CancerIQ's URL.
Which models can we request on this interface?
TC8 is the default if you send no model list. You can also request TC8CM (Tyrer-Cuzick 8 with competing mortality) and NCCN (HBOC genetic-testing criteria, Yes/No).
Who maintains the risk-model logic as guidelines update?
CancerIQ operates and maintains the underlying Tyrer-Cuzick model logic that powers the TC8 Calculator, so your team isn't required to rebuild or revalidate the calculation itself when a new guideline or model version is adopted.
Automated Tyrer-Cuzick 8 Breast Cancer Risk Assessment in Your EHR
Book a demo — we'll walk through how TC8 scores return directly into the Epic chart, then follow up with what it takes to configure the co nnection and a tailored implementation and pricing plan.
Evaluating another vendor? Bring us a documented quote and we'll work to match it.